Biozid Triclosan wirkt immunmodulierend

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Synthesis, leishmanicidal and cytotoxic activity of triclosan-chalcone, triclosan-chromone and triclosan-coumarin hybrids.

Twelve hybrids derived from triclosan were obtained via Williamson etherification of O-triclosan alkyl bromide plus chalcone and O-coumarin or O-chromone alkyl bromide plus triclosan, respectively. Structures of the products were elucidated by spectroscopic analysis. The synthesized compounds were evaluated for antileishmanial activity against L. (V) panamensis amastigotes. Cytotoxic activity w...

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ژورنال

عنوان ژورنال: Allergo Journal

سال: 2015

ISSN: 0941-8849,2195-6405

DOI: 10.1007/s15007-015-0939-z